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DNA結(jié)合抑制因子1重組兔單克隆抗體

產(chǎn)品貨號：

BN42154R
中文名稱：

DNA結(jié)合抑制因子1重組兔單克隆抗體
英文名稱：

Rabbit anti-ID1 Monoclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價

備注
BN42154R-50ul

50ul

￥2020.00

交叉反應(yīng)：Human 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF
BN42154R-100ul

100ul

￥3240.00

交叉反應(yīng)：Human 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF

產(chǎn)品描述

英文名稱	ID1
中文名稱	DNA結(jié)合抑制因子1重組兔單克隆抗體
別名	bHLHb24; Class B basic helix-loop-helix protein 24; DNA binding protein inhibitor ID 1; DNA binding protein inhibitor ID1; DNA-binding protein inhibitor ID-1; Dominant negative helix loop helix protein; ID 1; ID; ID1; ID1_HUMAN; Inhibitor of Differentiation 1; Inhibitor of DNA binding 1.
研究領(lǐng)域	腫瘤細胞生物染色質(zhì)和核信號信號轉(zhuǎn)導轉(zhuǎn)錄調(diào)節(jié)因子表觀遺傳學
抗體來源	Rabbit
克隆類型	Monoclonal
克隆號	5F1
交叉反應(yīng)	Human,
產(chǎn)品應(yīng)用	WB=1:300-1000 IHC-P=1:200-400 IHC-F=1:200-400 ICC=1:50-200 IF=1:50-200 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	16kDa
細胞定位	細胞核細胞漿
性狀	Lyophilized or Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human ID1:
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
產(chǎn)品介紹	ID proteins contain a helix-loop-helix (HLH) motif and regulate tissue-specific transcription within several cell lineages. They do not bind DNA directly, but inhibit lineage commitment by binding basic helix-loop-helix (bHLH) transcription factors through their HLH motif. ID proteins contribute to cell growth, senescence, differentiation and angiogenesis. Id1 mRNA is highly expressed in heart, lung and kidney and has lower expression in brain and liver. Two transcript variants encoding different isoforms have been found for this gene. Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. Subunit: Heterodimer with other HLH proteins. Interacts with COPS5. Subcellular Location: Cytoplasm. Nucleus. Similarity: Contains 1 bHLH (basic helix-loop-helix) domain. SWISS: P41134 Gene ID: 3397 Database links: Entrez Gene: 3397 Human Entrez Gene: 15901 Mouse Entrez Gene: 25261 Rat Omim: 600349 Human SwissProt: P41134 Human SwissProt: P20067 Mouse SwissProt: P41135 Rat Unigene: 504609 Human Unigene: 444 Mouse Unigene: 2113 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.